USMLE Step 1 Exam Pattern

USMLE Step 1 2021 will be an one-day exam of around 8 hours duration. The exam will comprise 7 different 60 minute blocks and cover the following topics:

  • Anatomy
  • Aging
  • Behavioral sciences
  • Biochemistry
  • Biostatistics and epidemiology
  • Genetics
  • Immunology
  • Microbiology
  • Molecular and cellular biology
  • Nutrition
  • Pathology
  • Pharmacology
  • Physiology

USMLE 2021 Step 1 Exam Pattern

Step and purpose Format
It accesses a candidate’s
understanding of and ability to apply important concepts of the basic sciences to the practice of medicine, with special emphasis on principles and mechanisms underlying health, disease, and modes of therapy There will be around 280 MCQs, split over seven 60-minute blocks
Mode of exam will be Computer-based that will be administered at Prometric test centers across the world Single day test
Duration of test Around eight hours

The USMLE Step 1 test content can be classified into the two dimensions of system and process. The broad categorization of the Step 1 test material can be done on the basis of these two dimensions.

USMLE Step 1 2021 Exam Pattern: System and Process

System Percentage of Test Content
General Principles of Foundational Science 15% - 20%
Immune System ; Blood & Lymphoreticular System ; Behavioral Health ; Nervous System & Special Senses ; Skin & Subcutaneous Tissue ; Musculoskeletal System ; Cardiovascular System ; Respiratory System ; Gastrointestinal System ; Renal & Urinary System ; Pregnancy, Childbirth, & the Puerperium ; Female Reproductive & Breast ; Male Reproductive ; Endocrine System 60% - 70%
Multisystem Processes & Disorders ; Biostatistics & Epidemiology ; Population Health ; Social Sciences 15% - 20%
Process Percentage of Test Content
Normal Processes 10% - 15%
Abnormal Processes 55% - 60%
Principles of Therapeutics 15% - 20%
Other 10% - 15%